Triple negative breast cancer (TNBC) is a heterogeneous (mixed) group of breast cancer that does not express estrogen, progesterone, or HER2-neu receptors on its surface. It is less differentiated (more abnormal and unlike breast cells) than receptor-positive tumors and, most often, more aggressive. Treatment for TNBC is rapidly evolving as scientists are attempting to discover new treatment options and possible novel therapeutic targets. Currently, the most effective initial treatment option is chemotherapy, a fact that has been borne out by many rigorous studies over the course of several years. Through this site, I hope to provide some information and options related to diet and lifestyle that may help patients with TNBC optimize the ability of their body to repair following treatment. Some of these methods may also reduce the chances of recurrence and/or the development of new cancers. In no way are these suggestions intended to serve as alternatives to standard therapy. I will also attempt to examine and explain any new published research that could enhance our ability to conquer this disease.
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This controversial diet is centred around low carbohydrate intake (< 20g/d) and getting most calories (70%) from fat and the remainder from protein. The diet is gaining popularity in the media and with many physicians for its effects on insulin, IGF-1, and the immune system. I've been on this diet for a few months now and fasting for 72 hours around the time of chemotherapy doses (which was nasty on weekly chemo!). Has anyone else out there been looking at this diet or fasting/fasting mimicking diet as a way of helping the immune system boost its activity against cancer cells? Certainly more studies are needed, but the logic makes sense to me: starving cancer cells of sugar puts them into a different metabolic pattern, where they may be more susceptible to chemo and the immune system.
I just discovered this! While trying to avoid sweets, I really wanted to find a way to enjoy a taste of chocolate, so I added a Tbsp of Hershey's cocoa to my match tea with a splash of unsweetened vanilla soy milk. I ended up with a wonderful hot chocolate! Total fat about 2G or less, sugar content less than 3G!
It's hard to say. There was a recent study demonstating effectiveness for women taking Tamoxifen. However, TNBC is much different. Coffee is also relatively high in cystine. Cystine deprivation has caused TNBC cell death in the laboratory setting. Check out: Blocking Key Nutrient May Treat Aggressive Form of Breast Cancer, Study Suggests . Most meats and some fish have relatively high levels of cystine.